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Creators/Authors contains: "Grady, Connor_J"

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  1. ; ; ; ; ; ; ; ; ; ; et al (, Protein Science)
    Abstract Several hundreds of tons of gadolinium‐based contrast agents (GBCAs) are being dumped into the environment every year. Although macrocyclic GBCAs exhibit superior stability compared to their linear counterparts, we have found that the structural integrity of chelates is susceptible to ultraviolet light, regardless of configuration. In this study, we present a synthetic protein termed GLamouR that binds and reports gadolinium in an intensiometric manner. We then explore the extraction of gadolinium from MRI patient urine as a preventative measure for gadolinium pollution and investigate the viability of employing cost‐effective bioremediation techniques for treating contaminated water bodies. Based on promising results, we anticipate proteins such as GLamouR can be used for detecting and mining rare earth elements beyond gadolinium and hope to expand the biological toolbox for such applications. 
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  2. ; ; ; ; ; ; ; ; ; ; et al (, ACS Synthetic Biology)